PapenfussLab/proteindj

User friendly and accurate binder design pipeline

BoltzGen: Toward Universal Binder Design

HalluDesign, a hallucination-driven all-atom framework for the iterative co-optimization and co-design of protein sequences and structures by leveraging the forward pass of a structure prediction model

Generative model for protein binder design for protein and small molecule targets. Combines a pretrained flow-based generative model (built on La-Proteina) with inference-time optimization.

de novo design of high affinity biological binders

BindCraft modified to make PyRosetta use and installation optional: no license needed

A generative model for programmable protein design

Protein Engineering via Exploration of an Energy Landscape

Template-based protein design with Raygun