brentp/vcfexpress

vembrane filters, sorts, and transforms VCF records using python expressions

🧬 High-performance VCF file parser and reformatter with VEP annotation support. Converts complex VCF files to analyzable TSV format with intelligent transcript handling.

C++ library and cmdline tools for parsing and manipulating VCF files with python and zig bindings

Structural variant toolkit for VCFs

Library for manipulating genomic variants and predicting their effects

cython + htslib == fast VCF and BCF processing

Annotation of VCF variants with functional impact and from databases (executable+library)

VCF visualization interface

Generic human DNA variant annotation pipeline