RosettaCommons/RFD4-Proteina

A generative model for programmable protein design

Code for the DISCO model: General Multimodal Protein Design Enables DNA-Encoding of Chemistry

Biomolecular design by sampling from generative models

Template-based protein design with Raygun

Generative model for protein binder design for protein and small molecule targets. Combines a pretrained flow-based generative model (built on La-Proteina) with inference-time optimization.

Programmable Design of Functional Proteins from Natural Language

Protein design and sculpting using Rosetta and Deep learning methods (RFDiff and Alphafold2)

All-Atom (Including Hydrogen!) Ligand-Conditioned Protein Sequence Design & Sidechain Packing GNN